Sepsis is a major health issue that affects millions of people around the world every year. It's the leading cause of death globally, impacting about 49 million people and causing 11 million deaths annually. In the United States alone, sepsis affects over 2 million people each year, leading to long hospital stays and intensive care. The cost of treating sepsis in the U.S. tops $62 billion annually, making it not only a health crisis but a significant financial burden on our healthcare system.
Despite its prevalence, current treatments for sepsis are limited to stop the devastating inflammatory cascade of sepsis. This highlights a critical need for new treatments that can actually address the damaging mechanism of sepsis, improve patient outcomes, and reduce healthcare costs.
Acute Kidney Injury (AKI) is another serious condition that affects nearly 4 million Americans each year. Treating AKI is very expensive, costing up to $24 billion annually. For those with severe cases that require dialysis, hospital costs can soar to $42,000 per visit. These high costs show how important it is to find better ways to manage and treat AKI, to help both patients and the healthcare system.
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Eliaz Therapeutics is pioneering a groundbreaking medical device designed to selectively remove galectin-3 (Gal-3) from the bloodstream.
Galectin-3 is a crucial driver of immune dysregulation, inflammation and fibrosis across various acute and chronic conditions. Gal-3 blood levels in Sepsis and Acute Kidney Injury (AKI) correlate with disease outcome- mortality and multi organ failure. Studies in sepsis animal models show that removal of Gal-3 via apheresis significantly reduces the mortality from Sepsis, as well as multi organ damage.
XGAL-3® is a pioneering patented platform technology that selectively removes the root cause - Galectin-3 from the bloodstream through targeted therapeutic apheresis.
Find out how we have developed the technology to target and remove Gal-3 directly from the bloodstream.
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Galectin-3 (Gal-3) is a protein that is naturally produced by our bodies. However, its levels can increase over time due to factors like stress, injury, and aging. Extensive research, spanning over 3,000 studies, has shown that elevated Gal-3 levels play a significant role in a variety of health problems. Many common chronic conditions that affect us and our loved ones have been linked to the harmful effects of this protein.
